Jardetzky Lab Publications Since 1990

1998

• Jardetzky, O. (1998) "What Can NMR Tell us About Protein Motions?" In: Protein Dynamics, Function and Design, (O. Jardetzky and J.-F. Lefèvre, eds.), Plenum Press, New York, in press.

1997

• Gryk, M. R. and Jardetzky, O. (1997) "Flexibility and Function of the Escherichia coli trp Repressor," In: Biological NMR Spectroscopy, (J. L. Markley and S. J. Opella, eds.), Oxford University Press, Oxford, pp. 35-57.
• Jardetzky, O. (1997) "Simple Insights from the Beginnings of Magnetic Resonance in Molecular Biology," In: Biological NMR Spectroscopy, (J. L. Markley and S. J. Opella, eds.), Oxford University Press, Oxford, pp. 3-17.

1996

• Jardetzky, O. and Zheng, Z. (1996) "Solution Dynamics of the trp-Repressor Studied by NMR Spectroscopy," In: Dynamics and the Problem of Recognition in Biological Macromolecules, (O. Jardetzky and J.-F. Lefèvre, eds.), Plenum Press, New York, pp. 209-222.
• Jardetzky, O. (1996) "Protein Dynamics and Conformational Transitions in Allosteric Proteins," Prog. Biophys. Mol. Biol. 65, 171-219.
• Zheng, Z., Brockel, C., Ganter, B., Lipsick, J., Sasaki, M., Ogata, K., Nishimura, Y. and Jardetzky, O. (1996) "Amide Proton Exchange Rates in c-Myb DNA-Binding Domain," Quart. Magn. Reson. Biol. Med. 3:1, 33-45.
• Gryk. M. R., Jardetzky, O., Klig, L. S. and Yanofsky, C. (1996) "Flexibility of DNA Binding Domain of trp Repressor Required for Recognition of Different Operator Sequences," Protein Science 5, 1195-1197.
• Finucane, M. D. and Jardetzky, O. (1996) "The pH-dependence of Hydrogen-Deuterium Exchange in trp Repressor: The exchange rate of amide protons in proteins reflects tertiary interactions, not only secondary structure," Protein Science 5, 653-662.
• Jardetzky, O. (1996) "NMR in Molecular Biology - a History of Basic Ideas," In: Encyclopedia of Nuclear Magnetic Resonance. Volume 1. Historical Perspectives, (D. M. Grant and R. K. Harris, eds.), John Wiley & Sons, Sussex, UK, pp. 402-408.
• Jardetzky, O. (1996) "Biological Macromolecules," In: Encyclopedia of Nuclear Magnetic Resonance. Volume 2 (A-COM), (D. M. Grant and R. K. Harris, eds.), John Wiley & Sons, Sussex, UK, pp. 901-920.
• Jardetzky, O. and Schmitt, T. H. (1996) "Biological Macromolecules: NMR Parameters," In: Encyclopedia of Nuclear Magnetic Resonance. Volume 2 (A-COM), (D. M. Grant and R. K. Harris, eds.), John Wiley & Sons, Sussex, UK, pp. 921-932.
• Gryk, M. R. and Jardetzky, O. (1996) "AV77 Hinge Mutation Stabilized the Helix-Turn-Helix Domain of trp Repressor," J. Mol. Biol. 255, 204-214.
• Jardetzky, O. and Schmitt, T. H. (1996) "Dynamics and Function of Proteins: What Can NMR Tell Us?" Chemtracts Biochem. & Mol. Biol. 6, 1-17.

1995

• Schmitt, T. H., Zheng, Z. and Jardetzky, O. (1995) "Dynamics of Tryptophan Binding to Escherichia coli trp Repressor Wild Type and AV77 Mutant: An NMR Study," Biochemistry 34, 13183-13189.
• Jardetzky, O. (1995) "Dynamics and Function of Allosteric Proteins," In: Proceedings of the International Conference on Molecular Structural Biology. (A. J. Kungl, P. J. Andrew and H. Schreiber, eds.), Gesellschaft Osterreichischer Chemiker, Wien, Austria, pp. 69-72.
• Finucane, M. D. and Jardetzky, O. (1995) "Mechanism of Hydrogen-Deuterium Exchange in trp Repressor Studied by ¹H-¹⁵N NMR," J. Mol. Biol. 253, 576-589.
• Zheng, Z., Gryk, M. R., Finucane, M. D. and Jardetzky, O. (1995) "Investigation of Protein Amide Proton Exchange by ¹H Longitudinal Spin Relaxation," J. Magn. Reson., Ser. B 108, 220-234.
• Zhao, D. and Jardetzky, J. (1995) "Simulated Annealing in the Calculation of NMR Structures," In: Adaptation of Simulated Annealing to Chemical Optimization Problems, (J. H. Kalivas, ed.), Elsevier Science B.V., Amsterdam, pp. 303-328.
• Zheng, Z., Czaplicki, J. and Jardetzky, O. (1995) "Backbone Dynamics of trp Repressor Studied by ¹⁵N NMR Relaxation," Biochemistry 34, 5121-5223.
• Gryk, M. R., Finucane, M. D., Zheng, Z. and Jardetzky, O. (1995) "Solution Dynamics of the trp Repressor. A Study of Amide Proton Exchange by T₁ Relaxation," J. Mol. Biol. 246, 618-627.

1994

• Jardetzky, O. (1994) "Wandern und Wissenschaft," In: Grazer Universitätsreden Ehrenpromotion von Univ.-Prof. Oleg Jardetzky zum Doktor der Gesamten Heilkunde, Verlag Jos. A. Kienreich, Graz, v. 53, pp. 17-30.
• Altman, R. B., Hughes, C., Zhao, D. and Jardetzky, O. (1994) "Compositional Characteristics of Relatively Disordered Regions in Proteins," Protein and Peptide Lett. 1, 120-127.
• Sze, D. Y. and Jardetzky, O. (1994) "High-Resolution Proton NMR of Cellular Extracts," ImmunoMethods 4, 113-126.
• Zhao, D. and Jardetzky, O. (1994) "An Assessment of the Precision and Accuracy of Protein Structures Determined by NMR -- Dependence on Distance Errors," J. Mol. Biol. 239, 601-607.
• Zhang, H., Zhao, D., Revington, M., Lee, W., Jia, X., Arrowsmith, C. and Jardetzky, O. (1994) "The Solution Structures of trp Repressor-Operator DNA Complex," J. Mol. Biol. 238, 592-614.
• Jardetzky, O. and Lefèvre. J.-F. (1994) "Protein Dynamics," FEBS Lett. 338, 246-250.

1993

• Kim, Y.H., Wade-Jardetzky, N.G. and Jardetzky, O. (1993) "¹H NMR and Histologic Analyses of Cutaneous Malignant Neoplasms: Standardization Factors Crucial for Maximizing Reproducibility and Interpretation of In Vivo Tumor Spectra," J. Magn. Res. in Biol. & Med. 1, 35-48.
• Altman, R.B., Pachter, R. and Jardetzky, O. (1993) "Structural Uncertainty of Proteins in Solution by NMR. A Re-Evaluation of the Structure of the Lac Repressor Headpiece," J. Appl. Magn. Reson. 4, 441-460.
• Zhao, D. and Jardetzky O. (1993) "Sequential Simulated Annealing: An Efficient Procedure for Structural Refinement Based on NMR Constraints," J. Phys. Chem. 97, 3007-3012.
• Zhao, D., Arrowsmith, C.H., Jia, X. and Jardetzky, O. (1993) "Refined Solution Structures of the E. coli trp Holo- and Aporepressor," J. Mol. Biol. 229, 735-746.

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1992

• Liu, Y., Zhao, D., Altman, R. and Jardetzky, O. (1992) "A Systematic Comparison of Three Structure Determination Methods from NMR Data: Dependence upon Quality and Quantity of Data," J. Biomol. NMR 2, 373-388.
• Pachter, R., Arrowsmith, C.H. and Jardetzky, O. (1992) "The Effect of Selective Deuteration on Magnetization Transfer in Larger Proteins," J. Biomol. NMR 2, 183-194.
• Koehl, P., Lefèvre, J.-F. and Jardetzky, O. (1992) "Computing the Geometry of a Molecule in Dihedral Angle Space using NMR Derived Constraints: A New Algorithm Based on Optimal Filtering," J. Mol. Biol. 223, 299-315.

1991

• Czaplicki, J., Arrowsmith, C. and Jardetzky, O. (1991) "Segmental Differences in the Stability of the trp-Repressor Peptide Backbone," J. Biomol. NMR 1, 349-361.
• Jardetzky, O. (1991) "Interpretation of NMR Data in Terms of Protein Structure," In: Computational Aspects of the Study of Biological Macromolecules by NMR Spectroscopy (J.C. Hoch, F.M. Poulsen & C. Redfield, eds.) Plenum Publ. Corp., New York, p. 375-390.
• Altman, R., Arrowsmith, C., Pachter, R. and Jardetzky, O. (1991) "Determination of Large Protein Structures from NMR Data: Definition of the Solution Structure of the trp Repressor," In: Computational Aspects of the Study of Biological Macromolecules by NMR Spectroscopy (J.C. Hoch, F.M. Poulsen & C. Redfield, eds.) Plenum Publ. Corp., New York, p. 363-374.
• Arrowsmith, C., Pachter, R., Altman, R. and Jardetzky, O. (1991) "The Solution Structures of E. coli trp Repressor and trp Aporepressor at an Intermediate Resolution," Eur. J. Biochem. 202:2, 53-66.
• Schutz, T., González-Méndez, R., Nabseth, D.C., Tune, B.M., Jardetzky, O. and Stevenson, D.K. (1991) "A Study of Cephaloridine-induced Acute Tubular Necrosis with ³¹P Magnetic Resonance Spectroscopy," Magn. Res. in Med. 18, 159-168.
• Pachter, R., Altman, R.B., Czaplicki, J. and Jardetzky, O. (1991) "Comparison of the NMR Solution Structure of Cyclosporin A Determined by Different Techniques," J. Magn. Res. 92, 468-479.
• Arrowsmith, C. H., Czaplicki, J., Iyer, S.B. and Jardetzky, O. (1991) "Unusual Dynamic Features of the trp-Repressor from E. coli," J. Am. Chem. Soc. 113, 4020-4022.

1990

• Pachter, R., Altman, R.B. and Jardetzky, O. (1990) "The Dependence of a Protein Solution Structure on the Quality of the Input NMR Data. Application of the Double-Iterated Kalman Filter Technique to Oxytocin," J. Magn. Res. 89, 578-584.
• Sze, D.Y. and Jardetzky, O. (1990) "Characterization of Lipid Composition in Stimulated Human Lymphocytes by ¹H-NMR," Biochim. Biophys. Acta. 1054, 198-206.
• Sze, D.Y. and Jardetzky, O. (1990) "Determination of Metabolite and Nucleotide Concentrations in Proliferating Lymphocytes by ¹H-NMR Acid Extracts," Biochim. Biophys. Acta. 1054, 181-197.
• Nabseth, D.C., González-Méndez, R., Schutz, T., Wade-Jardetzky, N., Tune, B.M., Jardetzky, O. and Stevenson, D.K. (1990) "Use and Limitations of Magnetic Resonance Spectroscopy to Assess Ischemic and Toxic Renal Damage: Review of Preliminary Experimental Studies," Pediatric Rev. Commun. 4, 151-156.
• Arrowsmith, C.H., Pachter, R., Altman, R.B., Iyer, S. and Jardetzky, O. (1990) "Sequence Specific ¹H NMR Assignments and Secondary Structure in Solution of E. Coli trp Repressor," Biochemistry 29, 6332-6341.
• Altman, R.B., Pachter, R., Carrara, E.A. and Jardetzky, O. (1990) "PROTEAN - Part II: Molecular Structure Determination from Uncertain Data," QCPE Bulletin 10:4, Program 596. Macintosh version: "PROTEAN II: Three-Dimensional Structures of Biological Macromolecules," QCPE Bulletin 10:3, QMAC016.
• Carrara, E.A., Brinkley, J.F., Cornelius, C.C., Altman, R.B., Brugge, J., Pachter, R., Buchanan, B. and Jardetzky, O. (1990) "PROTEAN - Part I: Generating Ensembles of Stylized Molecular Fragments using Uncertain Constraints," QCPE Bulletin 10:4, Program 596.
• Arrowsmith, C.H., Treat-Clemons, L., Szilágyi, L., Pachter, R. and Jardetzky, O. (1990) "The Use of Selective Deuteration for the Sequence Specific ¹H NMR Assignment of Larger Proteins," In: Die Makromolekulare Chemie, Macromolecular Symposia, vol. 34, (H. Höcker and B. Sedlácek, eds.) Hüthig & Wepf Verlag, Basel, p. 33-46.

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