Biochemistry 201

Advanced Molecular Biology

January 12, 2000

Doug Brutlag

Protein Structure & Folds Handout

Protein Structure Slides

Protein Fold Slides

Protein Structure Voet and Voet Chapter 6

Internet Resources

 

RasMol & Chime Distribution

Kinemage Distribution

Protein Kinemages

SCOP Protein Fold Database

SCOP Database from MRC (England)

CATH Protein Classification Database

DALI Protein Fold Database

LOCK: Structure Superposition

3D Structure Similarity Search

NCBI Structure Database

PDB Structure Database

Molecules R US

References

Bairoch, A. and Apweiler, R. (2000). The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 2000. Nucleic Acids Res, 28(1), 45-48.

Hofmann, K., Bucher, P., Falquet, L. and Bairoch, A. (1999). The PROSITE database, its status in 1999. Nucleic Acids Res, 27(1), 215-219.

Lo Conte L, Ailey B, Hubbard TJ, Brenner SE, Murzin AG, Chothia C. (2000) SCOP: a Structural Classification of Proteins database. Nucleic Acids Res. 2000 Jan 1;28(1):257-259.

Branden, C. & Tooze, J. Introduction to Protein Structure, Second Edition, Garland Publishing, New York.

Creighton, T. E. (1993). Proteins: Structures and Molecular Properties. (Second Edition ed.). New York: Freeman.

Creighton, T. E. (Ed.). (1992). Protein Folding. New York: W. H. Freeman & Co.

Darby, N. J., & Creighton, T. E. (1993). Protein Structure. Oxford: IRL Press.

Henikoff, S. And Henikoff, J.G. (1991) "Automated assembly of protein blocks for database searching" Nucleic Acids Res., 19, 6565&endash;6572.

Holm, L. and Sander, C. (1997). Dali/FSSP classification of three-dimensional protein folds. Nucleic Acids Res, 25(1), 231-4.

Hutchinson, E. G. and Thornton, J. M. (1996). PROMOTIF--a program to identify and analyze structural motifs in proteins. Protein Sci, 5(2), 212-20.

Nevill-Manning, C., Sethi, K., Wu, T. D. and Brutlag, D. L. (1997). Enumerating and Ranking Discrete Motifs. ISMB-97, 4, 202-209.

Nevill-Manning, C. G., Wu, T. D. and Brutlag, D. L. (1998). Highly Specific Protein Sequence Motifs for Genome Analysis. Proc. Natl. Acad. Sci. USA, 95(11), 5865-5871.

Orengo, C. A., Michie, A. D., Jones, S., Jones, D. T., Swindells, M. B. and Thornton, J. M. (1997). CATH--a hierarchic classification of protein domain structures. Structure, 5(8), 1093-108.

Schulz, G. E., & Schirmer, R. H. (1985). Principles of Protein Structure. New York: Springer-Verlag.

Stryer, L. (1995). Biochemistry. (Fourth Edition ed.). New York: W. H. Freeman & Co.