Eukaryotic Translation

 

Biochemistry 201

Advanced Molecular Biology

Prof. Peter Sarnow

 February 23, 2000

Eukaryotic Translation Handout

Eukaryotic Translation Slides

Literature References

Belsham G.J. and Sonenberg N. (1996) RNA-protein interactions in regulation of picornavirus RNA translation. Microbiol Rev 60(3):499-511.

Chen, C., and Sarnow, P. (1995). Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs. Science 268, 415-417.

Gallie, D. R. (1991). The cap and the poly(A) tail function synergistically to regulate mRNA translational efficiency. Genes Dev., 5, 2108-2116.

Hentze, M.W. (1997). eIF4G: a multipurpose ribosome adapter? Science 275, 500-501.

Hershey, J. W. B., Mathews, M. B., and Sonenberg, N. (1996). Translational Control. Cold Spring Harbor: Cold Spring Harbor Laboratory Press.

Jackson, R. J., and Kaminski, A. (1995). Internal initiation of translation in eukaryotes: the picornavirus paradigm and beyond. RNA 1, 985-1000.

Merrick, W.C. and Hershey, J.W.B. (1996). The pathway and mechanism of eukaryotic protein synthesis. In Translational control, J. W. B. Hershey, M. B. Mathews and N. Sonenberg, eds. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press), 31-69.

Pestova, T. V., Hellen, C. U. T., and Shatsky, I. N. (1996a). Canonical eukaryotic initiation factors determine initiation of translation by internal ribosome entry. Mol. Cell. Biol. 16, 6859-6869.

Pestova, T. V., Shatsky, I. N., and Hellen, C. U. T. (1996b). Functional dissection of eukaryotic initaion factor 4F; the 4A subunit and the central domain of the 4G subunit are sufficient to mediate internal entry of 43S preinitiation complexes. Mol. Cell. Biol. 16, 6870-6878.

Sachs, A. B. and Davis, R. W. (1989). The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation. Cell, 58, 857-67.

Stebbins-Boaz, B., Q. Cao, C. H. de Moor, R. Mendez, and J. D. Richter. 1999. Maskin is a CPEB-associated factor that transiently interacts with elF-4E. Mol Cell 4:1017-27.

Tarun, S. and Sachs, A. B. (1995). A common function for mRNA 5' and 3' ends in translation initiation in yeast. Genes and Dev., 9, 2997-3007.

Tarun, S. Z. and Sachs, A. B. (1996). Association of the yeast poly(A) tail binding protein with translation initiation factor eIF4G. EMBO, 15, 7168-7177

Tarun, S. Z. and Sachs, A. B. (1997). Translation initiation factor eIF4G mediates poly(A) tail-dependent translation. Proc. Natl. Acad. Sci. USA, submitted.