Maduke Lab Publications:

Elvington SM, Liu CW, Maduke MC. Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR. EMBO J. 2009 Oct 21;28(20):3090-102. PMID: 19745816

Lísal J, Maduke M. Proton-coupled gating in chloride channels. Philos Trans R Soc Lond B Biol Sci. 2009 Jan 27;364(1514):181-7. PMID: 18957380

Elvington SM, Maduke M. Thinking outside the crystal: Complementary approaches for examining transporter conformational change. Channels (Austin). 2008 Sep 23;2(5). PMID: 18989097

Lísal J, Maduke M. The ClC-0 chloride channel is a 'broken' Cl(-)/H(+) antiporter. Nat Struct Mol Biol. 2008 Jul 20. PMID: 18641661

Martinez GQ, Maduke M. A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membrane. PLoS ONE. 2008 Jul 23;3(7):e2746. PMID: 18648499

Matulef K, Howery AE, Tan L, Kobertz WR, Du Bois J, Maduke M. Discovery of potent CLC chloride channel inhibitors. ACS Chem Biol. 2008 Jul 18;3(7):419-28. PMID: 18642799

Engh AM, Faraldo-Gomez JD, Maduke M. The Role of a Conserved Lysine in Chloride- and Voltage-dependent ClC-0 Fast Gating. J Gen Physiol. 2007 Oct;130(4):351-63. PMID: 17846165

Engh AM, Faraldo-Gomez JD, Maduke M. The Mechanism of Fast-Gate Opening in ClC-0. J Gen Physiol. 2007 Oct;130(4):335-49. PMID: 17846164

Matulef K, Maduke M. The CLC 'chloride channel' family: revelations from prokaryotes. Mol Membr Biol. 2007 Sep-Dec;24(5-6):342-50. PMID: 17710638

Engh, A.M. and Maduke, M. (2005). Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule. J. Gen. Physiol. 125, 601-17.

Matulef, K. and Maduke, M. (2005). Side-dependent inhibition of a prokaryotic ClC by DIDS. Biophys. J. Sep;89(3):1721-30. PMID: 1599490

Mindell JA, Maduke M, Miller C, Grigorieff N. Projection structure of a ClC-type chloride channel at 6.5 A resolution. Nature. 2001 Jan 11;409(6817):219-23. PMID: 11196649

Mindell JA, Maduke M. ClC chloride channels. Genome Biol. 2001;2(2):REVIEWS3003. PMID: 11182894

Maduke M, Miller C, Mindell JA. A decade of CLC chloride channels: structure, mechanism, and many unsettled questions. Annu Rev Biophys Biomol Struct. 2000;29:411-38. PMID: 10940254

Maduke M, Pheasant DJ, Miller C. High-level expression, functional reconstitution, and quaternary structure of a prokaryotic ClC-type chloride channel. J Gen Physiol. 1999 Nov;114(5):713-22. PMID: 10539975

Maduke M, Williams C, Miller C. Formation of CLC-0 chloride channels from separated transmembrane and cytoplasmic domains. Biochemistry. 1998 Feb 3;37(5):1315-21. PMID: 9477958