Postal Address:

Express courier address:

Telephone: 650-723-7984
Fax: 650-723-6853
Email: john.boothroyd@stanford.edu

1972-1975 McGill University, Montreal, Canada.

1975-1979 Edinburgh University, Edinburgh, Scotland.

1979-1982 Scientist, Immunochemistry/Molecular Biology Department, Wellcome Research Laboratories, Beckenham, Kent, U.K.

1982-1988 Assistant Professor, Department of Microbiology and Immunology (formerly Medical Microbiology), School of Medicine, Stanford University, California.

1988-1994 Associate Professor, Department of Microbiology and Immunology, School of Medicine, Stanford University, California.

1994-1999 Professor and Co-Chairman, Department of Microbiology and Immunology, School of Medicine, Stanford University, California.

1999-2002 Professor and Chairman, Department of Microbiology and Immunology, School of Medicine, Stanford University, California.

2002-date Professor, Department of Microbiology and Immunology, and Senior Associate Dean for Research, School of Medicine, Stanford University, California.

1974-75 McGill University, Canada. Working with Drs. S.P. Gibbs and R.A. Cattolico on the physiology and biochemistry of the unicellular alga, Olisthodiscus luteus.

1975-79 University of Edinburgh, Scotland. Working with Dr. R.S. Hayward on the structure and function of regulatory signals located near the end of the early region of the coliphage T7 genome.

1979-1982 Wellcome Research Laboratories, Beckenham, England. Responsible for the application of recombinant DNA technology to two areas of research: 1. mechanism of antigenic variation in Trypanosoma brucei; 2. recombinant vaccines for Foot and Mouth Disease Virus;

1982-date Stanford University, California. Molecular biology of antigenic variation, trans-splicing and gene regulation in Trypanosoma brucei and on the cell and developmental biology of Toxoplasma gondii.

[1990-1991] M.R.C. Laboratory for Molecular Biology, Cambridge, England. Sabbatical with Dr. Hugh Pelham on the genetics and cell biology of a model system (yeast) in order to bring those approaches to our trypanosome and Toxoplasma work.

[1996] Dept. Pathology, Univ. Oxford, England and INSERM Unite 42, Lille, France. Sabbatical with Drs. David Ferguson (Oxford) and Jean-Francois Dubremetz (Lille) on imaging the ultrastructure of Toxoplasma.

1972-1973 Ontario Scholarship, Ontario Government.
1974-1975 University Scholarship, McGill University.
1975-1976 Moyse Traveling Award, McGill University.
1976-1978 Sir Arthur Sims Memorial Scholarship, Royal Society of Canada.
1976-1979 Overseas Science Research Scholarship, Royal Commission for the Exhibition of 1851.
1977 Rennie Bequest, Edinburgh University.
1977 Travel Award, NATO/EMBO.
1983-1984 Mellon Foundation Fellow, Stanford University.
1984-1986 Special Fellowship - Molecular Parasitology, Burroughs Wellcome Fund.
1984-1986 Hume Faculty Scholar, Stanford University.
1986-1991 Burroughs Wellcome Scholar in Molecular Parasitology.
1987-1988 Mellon Foundation Fellow, Stanford University
1990-1991 Fogarty Senior International Fellowship
1994 Scaife Lecturer, University of Edinburgh
1994 Nelson Lecturer, Montana State University
1994 Australian Society of Parasitology Invited Lectureship
1994-2004 MERIT Award, NIH
1999 Elected Chair of Gordon Conference on Parasitism
2002 Dunlevie Family University Fellow in Undergraduate Education, Stanford University
2002-2006 Senior Scholar in Global infectious Diseases, Ellison Medical Foundation.

Editor:

Member editorial board:

Ad hoc study section member for NIH - Tropical Medicine and Parasitology Study Section (10/93, 6/94, 6/97, 6/99, 2/02) and RFA-Infectious Etiology of Chronic Disease (10/01).

NIH Reviewers Reserve (1994-date)

Member, Joint Steering Committee, Scientific Working Group on African Trypanosomiasis, UNDP/World Bank/WHO (1988-1990).

Member, External Review Committee, ILRAD, Nairobi, Kenya (1988)

Member, University of California - Universitywide AIDS Research Program, Clinical Sciences Panel (1995)

Member, Molecular Parasitology Advisory Committee, Burroughs Wellcome Fund (1996-1999)

Chair, Molecular Parasitology Adv. Committee, Burroughs Wellcome Fund (1999-2001)

Member, Scientific Review Committee, Seattle Biomedical Research Institute (1999).

Organizer, West Coast Kinetoplastid Meeting, Asilomar (1988)

Co-organizer, International Toxoplasma Symposium, New Hampshire (1990)

Instructor, Marine Biological Laboratory Summer Course in "Biology of Parasitism", Woods Hole (1990)

Director, Marine Biological Laboratory Summer Course in "Biology of Parasitism: Modern Approaches", Woods Hole (1991-93)

Co-organizer, Society of Protozoology - Toxoplasma Workshop, Cleveland (1994)

Chair, Gordon Research Conference on Parasitism (1999)

University level:

School of Medicine:

Department of Microbiology and Immunology:

[amounts are Direct Costs for current year]

RO1 AI-41014 (John C. Boothroyd) 4/1/97 - 3/31/06 25% effort

NIH/NIAID $ 175,000

"Developmental Biology of Toxoplasma"

The major goals of this project are to identify key genes involved in the differentiation of Toxoplasma gondii tachyzoites to bradyzoites.

R37 AI-21423 (John C. Boothroyd) 8/1/84 - 4/30/04 25% effort

NIH/NIAID $243,796

"Antigens of Toxoplasma gondii and their Genes."

The major goals of this project are to study the Toxoplasma major surface antigen (SAG1) and ROP1 with particular emphasis on the regulation of their expression, their function and their biosynthesis.

RO1 AI45057 (John C. Boothroyd) 3/1/99-2/28/04 25% effort

NIH/NIAID $189,120

"Genetics of Invasion and Egress in Toxoplasma."

The major goals of this work are to study invasion and egress using mutants and complementation to identify the genes involved.

Foodborne Infection Program (John C. Boothroyd) 7/1/99 - 12/31/02 5% effort

Alameda County District Attorney’s Office. $68,309

"Strain-specific serological typing of Toxoplasma infection."The major goals of this work are to develop serological methods for distinguishing different strains in infected animals and people.

1. Boothroyd, J.C., Cross, G.A.M., Highfield, P., Winther, M. Rowlands, Brown, F. and Harris, T.J. Recombinant DNA expression vector encoding for foot and mouth disease virus proteins U.S. 4743554.

2. Burg, J.L., Pouletty, P.J. and Boothroyd, J.C. Selective Amplification of Target Polynucleotide Sequences. U.S. No. 5437990 and 6090951; EPO 0682120

3. Sibley, L.D., Buelow, R. and Boothroyd, J.C. Composition and method for distinguishing virulent and non-virulent Toxoplasma infections. U.S. No. 5429922

4. Burg, J.L., Kasper, L.H. and Boothroyd, J.C. Diagnostic Genes for Toxoplasmosis. U.S. No. 5629414; EPO 89903608.1

5. Burg, J.L., Kasper, L.H. and Boothroyd, J.C. P30 peptides of Toxoplasma gondii U.S. No. 5859196

6. Kim, K., Soldati, D. and Boothroyd, J.C. Transfection and genetic manipulations in obligate intracellular parasites. U.S. No. 5643718, 5976553