The Beckman Center for Molecular and Genetic Medicine
and Affymetrix
present a Public Policy Symposium

GENETIC TESTING: EXPECTATIONS, IMPLICATIONS AND OPTIONS

Thursday, October 10, 1995
8:30 to 5:00 PM
Fairchild Auditorium
Stanford University Medical Center


Hereditary disease and congenital defects are responsible for the hospitalization of 1.2 million persons annually in the United States. However, recent advances in genetics have made it possible to detect and diagnose an increasing number of human diseases, including the identification of genes that predispose people to common conditions such as hypertension, breast cancer and alcoholism. The development of therapies and prevention of disease through access to genetic information has profound consequences For the rising costs of health care and alleviating human suffering. But with the discoveries of the Human Genome Project and other biomedical research come ethical, legal and social issues of enormous complexity. What will 6e done with this new genetic information? Should insurers have access to a person's genetic profile? Should it be confidential? Who will set the standards For the performance of genetic testing? When should genetic testing occur? What laws are in place that may protect people against discrimination, and what laws will need to 6e changed? What is the corporate social responsibility for the manufacture and distri6ution of genetic testing products? Will genetic testing lead to modern-day eugenics? Please join us and a group of the nation's experts from industry and academia in a symposium and forum devoted to these critical issues.

Afternoon Symposium Schedule

Fairchild Auditorium

Time Topic Speaker
Colloquium: Diagnostics, Disease and Implications Fairchild Auditorium
1:00-1:15 p.m. Introduction Paul Berg
Director, Beckman Center
1:15-1:55 p.m. "Genome Impact on Drug Development" Thomas Caskey
Senior Vice-President, Research
Merck Research Laboratories
2:00-2:40 p.m. "The Evolution of Commercial Genetic Diagnostic Services: Risks, Regulation and Responsibility" George Poste
President, Research and Development
SmithKline Beecham Pharmaceuticals
2:45-3:05 p.m. Break
3:05-3:45 p.m. "Previewing the Future-With No Rewind Button or Changing Channels" Nancy Wexler
Professor of Neuropsychology
Columbia University
4:00-4:40 p.m. "From Basic Research to Standard of Care-Pitfalls in the Diffusion of Genetic Tests" Neil Holtzman
Director, Genetics and Public Policy Studies
Johns Hopkins Medical Institutions

Evening Session

Annenberg Auditorium, Cummings Art Building

Time Topic Speaker
Public Forum: Ethical Dilemmas Annenberg Auditorium
Cummings Art Building
7:30-7:45 p.m. Introduction David Singer
President and CEO Affymetrix
7:45-9:15 p.m. Panel Discussion Moderator: Donald Kennedy
President Emeritus
Stanford University


Panel Participants, Evening Session:

  • Jerry Bishop , Wall Street Journal
  • Thomas Caskey, Merck Research Laboratories
  • David Cox, Stanford University Medical School
  • David Frohnmayer, University of Oregon
  • Dean Hamer, National Institutes oF Health, National Cancer Institute
  • Neil Holtzman, Johns Hopkins Medical Institutions
  • Henry Greely, Stanford Unversity Law School
  • Barbara Koenig, Center For Biomedical Ethics, Stanford University
  • George Poste, SmithKline Beecham Pharmaceuticals
  • Nancy Wexier, Columbia University
  • Ernie Young, Center For Biomedical Ethics, Stanford University

    For more information contact Chris Scott at (415) 723-7184


    The Beckman Center and the Program in Molecular and Genetic Medicine gratefully acknowledge the following contributions to the Second Public Policy Symposium :
  • Affymetrix
  • Glaxo
  • Hewlett Packard
  • SmithKline Beecham

  • Symposium Speakers

    Paul Berg, Ph.D., is Cahill Professor in Cancer Research and Director of the Beckman Center For Molecular and Genetic Medicine at Stanford University. He received the Nobel Prize in Chemistry in 1980 for his work on recombinant DNA. He is a member of the National Academy of Sciences, a fellow of the Royal Society and past Chairman of the Advisory Committee of the Human Genome Project.

    Jerry Bishop is the Deputy News Editor For the Wall Street Journal, New York. He has received awards For his science reporting from the American Heart Association, the American Association for the Advancement of Science and the National Association of Science Writers, among others. He co-authored Genome, a book about biogenetics.

    Thomas Caskey, M.D., EA.C.R, is the Senior Vice President, Research at Merck Research Laboratories and Adjunct Professor in the Department of Molecular and Human Genetics, Medicine, Biochemistry and Cell Biology at Baylor College of Medicine. He is a member of the National Academy of Sciences and serves on two government advisory panels on mapping the human genome.

    David Cox, M.D., Ph.D., is Professor of Genetics and Pediatrics and Co-Director of the Human Genome Center, Stanford University. His research centers on high- resolution maps of mammalian chromosomes. He is past Chairman of the Human Genome Committee and a member of the Ethical, Legal and Social Implications Working Group For the National Center for Human Genome Research.

    Dave Frohnmayer, J.D., is President of the Unversity of Oregon. He has been Oregon's Attorney General and has served three terms in the Oregon House of Representatives. He and his wife, Lynn, are Founders of the Fanconi Anemia Research Fund, Inc., which funds genetic research For this disease. He is one of the founding directors of the National Marrow Donor Program.

    Henry (Hank) Greely, J.D., is Professor of Law at StanFord University. A past clerk on the United State Court of Appeals and the United States Supreme Court, he serves on the Health Benefits Advisory Council to the California Public Employee Retirement System and chairs the ethics subcommittee on the North American Committee of the Human Genome Diversity Project

    Dean Hamer, Ph.D., is Chief, Section on Gene Structure and Regulation in the Laboratory of Biochemistry of the National Cancer Institute. His research has focused on drug and vaccine production and gene regulation. Most recently, he has discovered a genetic link to male sexual orientation. He is the co-author of the book The Science of Desire.

    Neil Hoitzman, M.D. is Professor of Pediatrics with joint appointments in Health Policy and Epidemiology at Johns Hopkins University. He was a policy analyst for the Congress Office of Technology Assessment and former Director of the Hereditary Disease Disorders Program of the State of Maryland. He is the co-author of Assessing Genetic Risks which explores policy issues raised by the Human Genome Project.

    Donald Kennedy, Ph.D. is Bing Professor of Environmental &ience and President emeritus of Stanford University. He has served as a Senior Consultant in the Office of &ience and Technology Policy, Executive Office of the President and Commissioner of the Food and Drug Administration. He is a member of the National Academy of Sciences, and helps direct the Environmental Studies Program at Stanford.

    Barbara Koenig, Ph.D. is Executive Director and Senior Research Scholar at Stanford University Center For Biomedical Ethics. Her research focuses on a number of projects on clinical topics of relevance to bioethics. She has served on the clinical ethics committees of several hospitals and long-term care facilities.

    George Poste, D.Sc., Ph.D., is President, Research and Development, of SmithKline Beecham Pharmaceuticals. He is a fellow in the Royal College of Veterinary Surgeons and the Royal College of Pathologists, London. He has served on Government committees for the NIH, the Office of Technology Assessment and the Departments of State, Commerce and Defense.

    Nancy Wexler, Ph.D. is Higgins Professor of Neuropsychology in the Departments of Neurology and Psychiatry, Columbia University. Her research includes the isolation of the gene for Huntington's Disease. She is a member of the Advisory Committee to the Human Genome Center at Lawrence Berkeley Laboratories and is Chair of the Ethical, Legal and Social Implications Working Group for the National Center for Genome Research.

    Ernie Young, Ph.D., is the Co-Director of the Center for Biomedical Ethics and Clinical Professor of Ethics in the Departments of Medicine and Pediatrics, Stanford University. He is co-author of A Time to be Born, A Time to Die: Ethics and Conflicts in An intensive Care Nursery and author of Alpha and Omega: Ethics at the Frontiers of Life and Death.