Some Recent Publications from the DB Faculty: 2003

Yamashita YM, Jones DL, Fuller MT. Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science. 2003 Sep 12;301(5639):1547-50.

Farkas RM, Giansanti MG, Gatti M, Fuller MT.The Drosophila Cog5 homologue is required for cytokinesis, cell elongation, and assembly of specialized Golgi architecture during spermatogenesis.
Mol Biol Cell. 2003 Jan;14(1):190-200

Stuart JM, Segal E, Koller D, Kim SK A Gene Coexpression Network for Global Discovery of Conserved Genetic Modules. Science. 2003 Aug 21

Graef IA, Wang F, Charron F, Chen L, Neilson J, Tessier-Lavigne M, Crabtree GR. Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons.
Cell. 2003 May 30;113(5):657-70.

Hori Y, Rulifson IC, Tsai BC, Heit JJ, Cahoy JD, Kim SK.
Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16105-10.

Settle SH Jr, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM.
Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30

McAdams HH, Shapiro L. A bacterial cell-cycle regulatory network operating in time and space. Science. 2003 Sep 26;301(5641):1874-7.

Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR 3rd, Nusse R. Wnt proteins are lipid-modified and can act as stem cell growth factors.
Nature. 2003 May 22;423(6938):448-52.

Zhu AJ, Zheng L, Suyama K, Scott MP. Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction. Genes Dev. 2003 May 15;17(10):1240-52.

Ko DC, Binkley J, Sidow A, Scott MP.The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2518-25.

Dougan ST, Warga RM, Kane DA, Schier AF, Talbot WS. The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development. 2003 May;130(9):1837-51

Hillers KJ, Villeneuve AM. Chromosome-Wide Control of Meiotic Crossing over in C. elegans. Curr Biol. 2003 Sep 16;13(18):1641-7.

Colaiacovo MP, MacQueen AJ, Martinez-Perez E, McDonald K, Adamo A, La Volpe A, Villeneuve AM.Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombination.
Dev Cell. 2003 Sep;5(3):463-74

Park IK, Qian D, Kiel M, Becker MW, Pihalja M, Weissman IL, Morrison SJ, Clarke MF.Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells.
Nature. 2003 May 15;423(6937):302-5

Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, Willert K, Hintz L, Nusse R, Weissman IL. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature. 2003 May 22;423(6938):409-14.

Some Recent Publications from the DB Faculty: 2002

Goldberg JL, Klassen MP, Hua Y, Barres BA. Amacrine-signaled loss of intrinsic axon growth ability by retinal ganglion cells.
Science. 2002 Jun 7;296(5574):1860-4

Barres BA. The rewards of science extend far beyond publication.
Nature. 2002 Mar 28;416(6879):365

Olave I, Wang W, Xue Y, Kuo A, Crabtree GR.
Identification of a polymorphic, neuron-specific chromatin remodeling complex. Genes Dev. 2002 Oct 1;16(19):2509-17.

Chi TH, Wan M, Zhao K, Taniuchi I, Chen L, Littman DR, Crabtree GR.
Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature. 2002 Jul 11;418(6894):195-9.

Crabtree GR, Olson EN. NFAT signaling: choreographing the social lives of cells. Cell. 2002 Apr;109 67-79

Tazuke SI, Schulz C, Gilboa L, Fogarty M, Mahowald AP, Guichet A, Ephrussi A, Wood CG, Lehmann R, Fuller MT. A germline-specific gap junction protein required for survival of differentiating early germ cells.
Development. 2002 May;129(10):2529-39.

Schulz C, Wood CG, Jones DL, Tazuke SI, Fuller MT. Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells. Development. 2002 Oct;129(19):4523-34

Gronewold TM, Kaiser D. act operon control of developmental gene expression in Myxococcus xanthus. J Bacteriol. 2002 Feb;184(4):1172-9

Roy PJ, Stuart JM, Lund J, Kim SK. Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans. Nature. 2002 Aug 29;418(6901):975-9

Rulifson EJ, Kim SK, Nusse R. Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes. Science. 2002 May 10;296(5570):1118-20

Kingsley DM Mutations in ANKH cause chondrocalcinosis. Am J Hum Genet. 2002 Oct;71(4):933-40.

Shapiro L, McAdams HH, Losick R. Generating and exploiting polarity in bacteria. Science. 2002 Dec 6;298(5600):1942-6.

Kozopas KM, Nusse R. Direct flight muscles in Drosophila develop from cells with characteristics of founders and depend on DWnt-2 for their correct patterning. Dev Biol. 2002 Mar 15;243(2):312-25

Viollier PH, Sternheim N, Shapiro L. A dynamically localized histidine kinase controls the asymmetric distribution of polar pili proteins. EMBO J. 2002 Sep 2;21(17):4420-8

MacQueen AJ, Colaiacovo MP, McDonald K, Villeneuve AM.
Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans. Genes Dev. 2002 Sep 15;16(18):2428-42

Colaiacovo MP, Stanfield GM, Reddy KC, Reinke V, Kim SK, Villeneuve AM. A targeted RNAi screen for genes involved in chromosome morphogenesis and nuclear organization in the Caenorhabditis elegans germline. Genetics. 2002 Sep;162(1):113-28

Weissman IL.
Stem cells--scientific, medical, and political issues.
N Engl J Med. 2002 May 16;346(20):1576-9.