Barres, Ben A.   
Developmental Biology and Neurosciences
Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system.
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Crabtree, Gerald R.   
Developmental Biology and Pathology
Morphogenesis and axonal outgrowth in the nervous system. The role of ATP-dependent chromatin remodeling complexes in development of the neurvous and immune systems.
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Fuller, Margaret T.   
Developmental Biology and Genetics                
Transcriptional and post transcriptional regulation of spermatogenesis; Cell morphogenesis and cell cycle control during differentiation; Genetic control of stem cell behavior.
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Recent Publications

Hogness, David S.   
Emeritus Professor of Developmental Biology and of Biochemistry 
Temporal and hormonal control of Drosophila development  

Kaiser, A. Dale   
Biochemistry, Cancer Biology and Developmental Biology
How are genes regulated to construct a developmental program? How do signals received from other cells change the program and coordinate it for multicellular development? The approach taken by our laboratory group to answer these questions utilizes biochemistry and genetics; genetics to isolate mutants that have particular defects in development and biochemistry to determine the molecular basis of the defects. We study fruiting body development in Myxococcus xanthus, a social bacterium.
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Kim, Seung K.   
Developmental Biology                    
We study morphogenesis and cell differentiation in the pancreas, an endoderm-derived organ, using molecular, embryologic and genetic methods in mice, chicks and human tissues. Our work suggests that critical epithelial-mesenchymal cell interactions during pancreas ontogeny are regulated by Hedgehog, FGF and TGF-ß signaling pathways. We wish to translate these basic studies into novel diagnostic and therapeutic strategies for diabetes mellitus and pancreas cancer.
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Kim, Stuart K.   
Developmental Biology and Genetics                
We study cell polarity and MAP kinase signaling in C. elegans. We have found that a complex of PDZ-containing proteins is required for basolateral localization of the LET-23 receptor in epithelial cells. We have identified genes regulated by MAP kinase signaling using DNA microarrays.
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Kingsley, David M.   
Developmental Biology                    
My laboratory uses a variety of genetic, cellular, and molecular approaches to study skeletal development in humans, mice, and fish. Many of our studies begin with classical genetic traits that disrupt normal skeletal development. By isolating the genes responsible for these traits, it should be possible to identify the key genetic pathways that underlie skeletal patterning, skeletal disease, and skeletal evolution in higher animals.
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Recent Publications
Lab Web Pages:
http://kingsley.stanford.edu
http://www.hhmi.org/research/investigators/kingsley.html

McAdams, Harley
Developmental Biology
We study the design and function of genetic regulatory networks from a total system perspective. We are particularly focused on the overall network that controls the cell cycle, asymmetric cell division, and metabolism of the bacterium Caulobacter crescentus. Methods we use include application of gene expression microarrays, bioinformatic analysis of genomic data, and modeling studies.
Lab Web Pages:
http://caulo.stanford.edu/usr/hm/

Nusse, Roeland 
Cancer Biology and Developmental Biology                
We are interested in the tole of the Wnt gene family in intercellular signaling during embryogenesis and tumorigenesis. We work on two Drosophila Wnt genes: wingless and DWnt-2. These genes have very specific phenotype in the fly. We use Drosophila genetics and cell culture assays to understand how these proteins work during embryogenesis. We have found that Frizzled proteins act as receptors for Wnts.
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Porzig, Ellen F.   
Developmental Biology and Molecular Pharmacology                

Scott, Matthew P.   
Developmental Biology, Genetics, Neurosciences and Cancer Biology        
We study regulators of transcription and signaling that control animal development and prevent cancerous growth. Particular areas include homeobox genes, hedgehog/patched signaling and its links to skin and brain cancer, chromatin gene regulation machines, and neural and heart development.
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Shapiro, Lucille   
Cancer Biology, Developmental Biology and Genetics            
A basic question in developmental biology involves the mechanisms used to generate the three-dimensional organization of a cell from a one-dimensional genetic code. Our goal is to define these mechanisms using both molecular genetics and biochemistry. The developmental program by which a single cell proceeds to a fully-developed organism involves........... Shapiro web page
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Recent Publications

Spudich, James A.   
Biochemistry and Developmental Biology        
Biochemical, molecular genetic, and structural studies of actin, myosin, and associated regulatory proteins from eukaryotic cells: Work focuses on the design and development of in vitro assays for ATP dependent movement of purified myosin on filaments reconstituted from purified actin. Myosin gene cloning and expression of site directed mutagenized forms, which are analyzed for altered functions, is also carried out. Emphasis is on the molecular basis of energy transduction that leads to myosin movements on actin filaments and on regulation of actin and myosin interactions and of their assembly states, with particular interest in Dictyostelium cytokinesis, and other forms of cell movement.
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Talbot, William S.   
Developmental Biology                    
We use genetic and genomic approaches to investigate the molecular basis of cell fate specification and morphogenesis in the zebrafish embryo.
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Villeneuve, Anne M.   
Developmental Biology and Genetics                
Mechanisms underlying pairing and recombination between homologous chromosomes during meiosis, using the nematode Caenorhabditis elegans as an experimental system. High-resolution 3-D imaging of meiotic chromosomes. Transgene-mediated cosuppression of germline gene expression.
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Recent Publications